Table 2.
Comorbidity and symptoms depending on histopathological classification
|
Collagenous colitis N = 92 |
Lymphocytic colitis N = 66 |
P-value | |
|---|---|---|---|
| Comorbidity | |||
|
Hypertension Missing value |
34 (37.0) 10 |
20 (30.3) 6 |
0.572 |
|
Rheumatoid arthritis Missing value |
18 (19.6) 13 |
15 (22.7) 9 |
|
|
Asthma and/or bronchitis Missing value |
16 (17.4) 11 |
9 (13.6) 12 |
0.632 |
|
Diabetes Missing value |
6 (6.5) 13 |
5 (7.6) 11 |
0.694 |
|
Celiac disease Missing value |
3 (3.3) 17 |
8 (12.1) 13 |
0.050 |
|
Gastric ulcer Missing value |
12 (13.0) 14 |
11 (16.7) 8 |
0.749 |
|
Thyroid disease Missing value |
16 (17.4) 15 |
12 (18.2) 10 |
1.000 |
|
Cancer Missing value |
10 (10.9) 15 |
3 (4.5) 11 |
0.770 |
| Drug treatment | |||
| Corticosteroids | 34 (37.0) | 14 (21.2) | 0.037 |
| Proton pump inhibitors | 23 (25.0) | 18 (27.3) | 0.854 |
| Selective serotonin reuptake inhibitors | 11 (12.0) | 19 (28.8) | 0.013 |
| Statins | 17 (18.5) | 11 (16.7) | 0.835 |
| Thyroid hormones | 15 (16.3) | 11 (16.7) | 1.000 |
| Gastrointestinal symptoms | |||
|
Abdominal pain 5 (1–15) |
35 (12–53) | 41 (12–57) | 0.196 |
|
Diarrhea 3 (0–10) |
40 (14–77) | 50 (26–73) | 0.289 |
|
Constipation 9 (1–22) |
6 (2–18) | 9 (4–28) | 0.085 |
|
Bloating and flatulence 14 (1–29) |
55 (20–77) | 55 (25–71) | 0.805 |
|
Vomiting and nausea 2 (0–3) |
7 (1–23) | 13 (2–38) | 0.130 |
|
Intestinal influence on daily life 2 (0–18) |
45 (12–74) | 42 (26–84) | 0.151 |
|
Psychological well-being 4 (0–16) |
26 (10–54) | 24 (10–50) | 0.751 |
Comorbidity reflects whether the patients ever have been treated for any of these diseases. Missing values mean that the participant has not answered the question whether they have had the disease or not in the questionnaire. Gastrointestinal symptoms were assessed by the Visual Analog Scale for Irritable Bowel Syndrome, 0–100 mm, where 0 represents no symptoms and 100 maximal symptoms [20]. Reference values for VAS-IBS from healthy women are shown within brackets [21]. Values are given as number and percentages or median and interquartile ranges. Mann–Whitney U test or Fisher´s exact test. P ≤ 0.05 was considered statistically significant