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Effect of MAb to MCP-1 on migration of monocytes across HUVEC stimulated with IL-1 or B. burgdorferi
| Expt | Stimulus | % Inhibition by anti-MCP-1a | P value |
|---|---|---|---|
| 1 | None | 88 ± 5 | 0.0095 |
| IL-1 | 63 ± 16 | 0.0073 | |
| B. burgdorferi | 5 ± 15 | NSb | |
| 2 | None | 93 ± 3 | <0.0001 |
| IL-1 | 64 ± 9 | 0.004 | |
| B. burgdorferi | 21 ± 13 | NS | |
| 3 | None | 92 ± 2 | <0.0001 |
| IL-1 | 67 ± 6 | 0.0004 | |
| B. burgdorferi | 49 ± 8 | 0.0043 |
Mean ± SD of three replicate samples.
NS, not significant.
