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The effect of PS on cytokine levels in cultured cells. Neuro-2A murine neuroblastoma and RAW264.7 murine microphage cells were co-cultured as in Methods and treated with paclitaxel or PS or both for 24 h, when the culture media were harvested. The levels of the four cytokines shown were determined in the culture media using the magnetic bead-based immunoassay kit as in Methods. Values are the average of duplicates that were within 11% of each other. *p < 0.01 compared to paclitaxel.
