Table 2.
Arm 1 | Arm 2 | Arm 3 | Overall trial | |
---|---|---|---|---|
OR (95% CI) | OR (95% CI) | OR (95% CI) | P | |
As randomized, unadjusted | 0.74 (0.58–0.94) | 0.94 (0.72–1.23) | 0.56 (0.44–0.71) | .02 |
As randomized, adjusted by no. of draws | 0.74 (0.58–0.95) | 0.93 (0.71–1.23) | 0.56 (0.44–0.71) | .02 |
As randomized, adjusted by no. of draws, age, sex, race, payer, surgery, and comorbidities | 0.73 (0.57–0.94) | 0.93 (0.7–1.22) | 0.55 (0.43–0.71) | .02 |
As treated, unadjusted | 0.74 (0.58–0.94) | 0.93 (0.71–1.22) | 0.56 (0.44–0.71) | .02 |
Randomization to all 3 arms, unadjusted | 0.75 (0.58–0.96) | 0.9 (0.68–1.19) | 0.56 (0.44–0.71) | .03 |
Accounting for randomization strata, unadjusted | 0.73 (0.58–0.94) | 0.94 (0.72–1.23) | 0.56 (0.44–0.71) | .02 |
Weekday draws (entire set collected on weekday) | 0.77 (0.57–1.05) | 0.82 (0.6–1.13) | 0.56 (0.41–0.76) | .18 |
Weekend draws (any in set collected on weekend) | 0.66 (0.44–0.99) | 1.2 (0.72–1.98) | 0.56 (0.39–0.83) | .06 |
Day draws (entire set collected 5 am–4:49 pm) | 0.71 (0.5–1.02) | 0.97 (0.68–1.39) | 0.64 (0.46–0.9) | .24 |
Night draws (any in set collected 5 pm–4:59 am) | 0.79 (0.56–1.11) | 0.9 (0.59–1.37) | 0.44 (0.31–0.62) | .01 |
NOTE. P values in the pairwise analysis were as follows: P = .19 for the comparison of arm 2 with arm 1; P = .11 for the comparison of arm 3 with arm 1; and P = .005 for the comparison of arm 3 with arm 2.