Figure 5.
The RL model fit to choice behavior indicates differential effects on inverse temperature and decay parameters between male and female rats during deterministic and probabilistic action-based reversals. Plotted are estimated model parameters for RL1decay fitted to each session during deterministic (100/0) (A) and probabilistic (90/10) (B) reversals. α = learning rate, β = inverse temperature, γd = decay rate for unchosen option. Drug order was counterbalanced such that on R2 and R4 (not shown) animals received VEH if they were administered CNO first on R1 and R3 and vice versa. The female eGFP group exhibited overall lower γd than male eGFP rats during the first deterministic R1. Chemogenetic inhibition of vlOFC increased γd on both reversals (R1 and R3) for female rats, whereas inhibition of BLA increased β on the first probabilistic R3 for female rats. Only comparisons with *p < 0.05.