Table 1.
Description of the study samples
| ACT brain donors, with baseline TBI-LOC and APOE ε4 data | ||||
|---|---|---|---|---|
|
|
||||
| Full Cohort (n = 5,546) n (%) |
No baseline TBI with LOCa (n = 626) n (%) |
Baseline TBI with LOCb (n = 154) n (%) |
Total (n = 780) n (%) |
|
|
| ||||
| Male | 2,318 (42%) | 246 (39%) | 87 (56%) | 333 (43%) |
| Age at last visit | ||||
| 68–84 | 3,442 (62%) | 242 (39%) | 62 (40%) | 304 (39%) |
| 85–89 | 1,170 (21%) | 181 (29%) | 47 (31%) | 228 (29%) |
| 90–94 | 697 (13%) | 149 (24%) | 29 (19%) | 178 (23%) |
| 95–106 | 237 (4%) | 54 (9%) | 16 (10%) | 70 (9%) |
| Completed college | 3,978 (72%) | 433 (69%) | 111 (72%) | 544 (70%) |
| APOE ε4 alleles | ||||
| None | 3,329 (60%) | 447 (71%) | 114 (74%) | 561 (72%) |
| 1–2 | 1,179 (21%) | 179 (29%) | 40 (26%) | 219 (28%) |
| Unknown | 1,038 (19%) | |||
| Any dementia, last visit | 1,270 (23%) | 286 (46%) | 69 (45%) | 355 (46%) |
| ACT study cohort | ||||
| 1994–1996 | 2,581 (47%) | 391 (62%) | 101 (66%) | 492 (63%) |
| Subsequent | 2,965 (53%) | 235 (38%) | 53 (34%) | 288 (37%) |
a
No TBI with LOC based on ACT study data, or, when available, on BISQ self-report or proxy or chart review.
b
At least one report of TBI with LOC as of ACT study entry, based on ACT study data, or, when available, on BISQ self-report or proxy or chart review.