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. Author manuscript; available in PMC: 2024 Feb 12.
Published in final edited form as: Nat Methods. 2023 Nov 16;21(1):37–40. doi: 10.1038/s41592-023-02082-9

Extended Data Figure 9. Impact of flexible domains on the global FSC curve.

Extended Data Figure 9

(A) Simulated density map of β-galactosidase, with two rigid subunits at 2.5Å and two flexible ones resolved at 15Å. (B) Same simulated map as A, with the two flexible subunits resolved at 7Å. (C) Comparison of “gold-standard” FSC curves of the two structures. Blue - A, red - B.