Skip to main content
. Author manuscript; available in PMC: 2024 Feb 12.
Published in final edited form as: Nat Methods. 2023 Nov 16;21(1):37–40. doi: 10.1038/s41592-023-02082-9

Fig. 2.

Fig. 2.

Refinement of the ABC transporter (EMPIAR-10374). (A) Reconstruction of the ABC transporter using original orientation assignment, colored by local resolution. (B) Continuous movement of the Fab shown in morphed molecular models. (C) Reconstruction of the ABC transporter after converting the movement trajectory to particle orientations, colored by local resolution. (D) Feature comparison at a β-sheet in the C-domain of Fab from the original structure (gray) and the structure after GMM-based refinement (pink).