Figure 3.

Retinal ON and OFF pathways have different contrast sensitivity when measured at 500 cd/m² luminance range. a, Retinal responses from subject S3 at luminance range 500 cd/m². Same format as in Figure 1. b, Contrast responses from subject S3 fitted with Naka–Rushton functions. c–f, Same as a and b for subjects S9 (c, d) and S14 (e, f). g, Scatterplot of C50n values from ON and OFF retinal pathways measured in 47 eyes from 26 human subjects. The top label reports Pearson’s correlation coefficient (r) next to the probability that the correlation is due to chance (p). The numbers below are means ± standard deviations for light (red) and dark stimuli (blue) next to the significance probability value (p) calculated with a two-sided Wilcoxon sign-rank test. The slope and intercept of a linear regression are reported below only for significant correlations (p values in bold). h–k, Same as g for exponent (h), response at maximum contrast (i), latency (j), and goodness of fit (k).