FIG. 2.

Effect of B. pertussis toxins on the release of ISF. PTx or PTxm was added to the incubation medium of macrophages (MφS) before and during stimulation with TxA. The cells were washed and incubated for a further 2 h without stimulation. The supernatants (SUP.) were subsequently tested on rabbit ileum in vitro. The results represent the mean ± SEM of the number (n) of preparations tested. ∗, the P value for SUP. MφS + TxA versus the control or SUP. MφS + TxA + PTx was determined by ANOVA (Bonferroni or Dunn method). The P value for SUP. MφS + TxA versus SUP. MφS + TxA + PTxm was not significant (Bonferroni or Dunn method).