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Inhibition of intestinal secretion by IL-1ra. Rabbit ileum was treated with IL-1ra for 30 min before the addition of supernatants (SUP.) from TxA-stimulated macrophages (MφS). Intestinal secretion was evaluated as described in Materials and Methods. The results represent the mean ± SEM of the number (n) of preparations tested. ∗, the P value for SUP. MφS + TxA versus the other two groups was determined by ANOVA (Bonferroni or Dunn method).
