TABLE 1.
Effects of EGF on live bacterial recovery from intestinal mucosal homogenates of rabbits infected for 7 days with E. coli RDEC-1
| Group (n) | Mean live bacterial recovery (log10 CFU/cm of gut) ± SEMa
|
|||
|---|---|---|---|---|
| Jejunum | Ileum | Proximal colon | Distal colon | |
| Infected untreated (10) | 4.19 ± 0.26 | 6.16 ± 0.26 | 4.92 ± 0.29 | 5.16 ± 0.19 |
| Infected EGF treated (9) | 3.10 ± 0.41* | 4.88 ± 0.23** | 4.01 ± 0.16* | 4.50 ± 0.28 |
| % Clearanceb | 92.0 | 94.7 | 85.5 | 78.0 |
a
Calculated from serial dilutions of homogenates plated onto MacConkey agar. No bacteria were recovered from any of the nine control rabbits. ∗, P < 0.05 untreated compared with EGF treated; ∗∗, P < 0.01 untreated compared with EGF treated.
b
Calculated from absolute numbers of bacteria recovered per centimeter of gut as (total number of bacteria in untreated sample/total number of bacteria in EGF-treated sample)/total number of bacteria in untreated sample.