Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Models linking transcription factor (TF) binding and transcriptional bursting.
Top, TF exchange model where TF exchange prolongs periods of high TF occupancy at the promoter, thereby increasing the burst duration. Bottom, multistep activation model where longer TF residence times initiate bursts more productively through a multistep transcriptional activation cascade, thereby increasing burst frequency.
