Table 1:
Immune function of the patients
| Patient 1 | Patient 2 | Patient 3 | Normal range | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Age (years) | 2.5 | 7 | 16 | 1 | 2 | 12 | 1 | 3 | |
| Markers (cells/µL) | |||||||||
| CD3 | 3277 | 2537 | 2318 | N/D | 2696 | 1637 | 2428 | 5518 | 700-4200 |
| CD4 | 3072 | 1577 | 1532 | N/D | 2081 | 1049 | 1862 | 4647 | 300-2000 |
| CD8 | 409 | 926 | 764 | N/D | 614 | 525 | 567 | 653 | 300-1800 |
| CD19/20 | 2185 | 411 | 23 | N/D | 2648 | 107 | 1255 | 1579 | 200-1600 |
| CD56 | 203 | 308 | 139 | N/D | 473 | 98 | 604 | 726 | 90-900 |
| Mitogen responses (% of control) | |||||||||
| PHA | N/D | 28 | 5 | N/D | 100 | 39 | 120 | 18 | >50% |
| aCD3 | N/D | 64 | <1 | N/D | 90 | 37 | 10 | 3 | >50% |
| Immunoglobulin (g/L) | |||||||||
| IgG | 18.3 | 9.1 | 5.61 | 19.2 | 16.8 | 12.9 | 15.3 | 10.6 | 5.0–14.6 |
| IgA | 0.2 | 0.75 | 0.24 | 0.375 | 3.38 | 0.45 | 0.17 | 1.53 | 0.3–2.0 |
| IgM | 4.9 | 0.8 | 0.82 | 1.06 | 1.22 | 0.72 | 4.09 | 0.23 | 0.2–2.5 |