Table 3.
Associations of plasma activin A with major adverse kidney events
Variables | Model 1 | Model 2 | Model 3 |
---|---|---|---|
HR (95% CI) | HR (95% CI) | HR (95% CI) | |
Plasma activin A, pg/ml | |||
Tertile 1: 220 (164–259)a | Reference | Reference | Reference |
Tertile 2: 382 (333–414)a | 3.17 (1.61 to 6.26) | 1.73 (0.86 to 3.52) | 1.48 (0.72 to 3.02) |
Tertile 3: 621 (525–754)a | 8.38 (4.43 to 15.85) | 3.10 (1.55 to 6.21) | 2.05 (0.98 to 4.27) |
Per 1-Ln increase | 5.06 (3.46 to 7.40) | 2.27 (1.40 to 3.68) | 1.64 (0.99 to 2.73) |
Model 1 is unadjusted. Model 2 is adjusted for age, sex, serum albumin, proteinuria, and baseline eGFR. Model 3 is Model 2 and further adjusted for primary clinicopathologic diagnosis. CI, confidence interval; HR, hazard ratio; Ln, natural logarithm.
Median (interquartile range).