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. 2023 Nov 20;19(2):169–177. doi: 10.2215/CJN.0000000000000365

Table 3.

Associations of plasma activin A with major adverse kidney events

Variables Model 1 Model 2 Model 3
HR (95% CI) HR (95% CI) HR (95% CI)
Plasma activin A, pg/ml
 Tertile 1: 220 (164–259)a Reference Reference Reference
 Tertile 2: 382 (333–414)a 3.17 (1.61 to 6.26) 1.73 (0.86 to 3.52) 1.48 (0.72 to 3.02)
 Tertile 3: 621 (525–754)a 8.38 (4.43 to 15.85) 3.10 (1.55 to 6.21) 2.05 (0.98 to 4.27)
 Per 1-Ln increase 5.06 (3.46 to 7.40) 2.27 (1.40 to 3.68) 1.64 (0.99 to 2.73)

Model 1 is unadjusted. Model 2 is adjusted for age, sex, serum albumin, proteinuria, and baseline eGFR. Model 3 is Model 2 and further adjusted for primary clinicopathologic diagnosis. CI, confidence interval; HR, hazard ratio; Ln, natural logarithm.

a

Median (interquartile range).