Table 2. Conversion of 5-Chloromethyltriazoles 7a–d into 5-Azidomethyltriazoles 1a–d.
| entry | compound | R1 | R2 | yield (%)a |
|---|---|---|---|---|
| 1 | 1a | H | H | 60 |
| 2 | 1b | Me | Me | 93 |
| 3 | 1c | Me | H | 91 |
| 4 | 1d | Cl | Me | 52 |
After isolation by column chromatography.
| entry | compound | R1 | R2 | yield (%)a |
|---|---|---|---|---|
| 1 | 1a | H | H | 60 |
| 2 | 1b | Me | Me | 93 |
| 3 | 1c | Me | H | 91 |
| 4 | 1d | Cl | Me | 52 |
After isolation by column chromatography.