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. 2024 Feb 12;14(2):e3373. doi: 10.1002/brb3.3373

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© 2024 The Authors. Brain and Behavior published by Wiley Periodicals LLC

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Calcitriol regulated microglial M1/M2 polarization and reduced pro‐inflammatory cytokines release. (a) Relative mRNA expression of indicated microglial M1 phenotypic markers in mesencephalic tissues. (b) Relative mRNA expression of indicated microglial M2 phenotypic markers in mesencephalic tissues. (c) Relative mRNA expression of IBA‐1. (d) Levels of TNF‐α in mesencephalic tissues. (e) Levels of IL1‐β in mesencephalic tissues. (f) Levels of IL‐6 in mesencephalic tissues. n = 5 per group. **p 〈 .01, ***p 〈 .001 compared to the sham operation group. #p 〈 .05, ##p 〈 .01, compared to the 6‐OHDA injection group. Data were analyzed by one‐way ANOVA with Tukey's posttest.