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. 2023 Dec 27;42(3):301–318. doi: 10.1007/s40273-023-01336-w

Table 3.

Methodological characteristics of studies (N = 43)

Item Detail Number of studies
n (%)
Study design Prospective 17 (39.53)
Retrospective 25 (58.14)
Both 1 (2.33)
Type of costing analysis Bottom-up 38 (88.37)
Top-down 4 (9.30)
Both 1 (2.33)
Perspective of studies Healthcare system (public, private) 23 (53.49)
Provider (hospital, clinic) 7 (16.28)
Societal 12 (27.91)
Patient 1 (2.33)
No data 1 (2.33)
Costs included Direct healthcare costs 42 (97.67)
Direct non-healthcare costs 13 (30.23)
Direct healthcare costs from patienta 12 (27.91)
Patient’s productivity lossa 3 (6.98)
Caregiver’s productivity lossa 9 (20.93)
Intensity of resources use last weeks of PC (yes) 20 (46.51)
Regression analysis (yes) 19 (44.19)
Sensitivity analysis (yes) 7 (16.28)
Exploring caregiving n = 10b
Valuation method informal caregivinga Opportunity costs method 10 (100)
Proxy good method
Several methods
Time method reveala Recall methods 2 (20)
Direct question 8 (80)
Time of caregiving activities detailed (yes)c 2 (20)

PC palliative care

aFrom those that report patient’s productivity loss, societal perspective was adopted in two studies [1, 2] and patients’ perspective in one study [3]

bFrom studies that report caregiving (n = 10)

cThe detail denotes the time devoted to care. Only Chai et al. [4] and Brick et al. [5] list some activities (see text for details)