Table 2.
The list of 12 markers of AD associated neurotoxic astrocytes
| UniProt ID | Gene Symbol | Gene Name | Function |
|---|---|---|---|
| Q5VZM2 | GNG12 | protein G-protein subunit gamma 12 | G-protein signaling modulator |
| Q07352 | ZFP36L1 | Zinc finger protein 36-like 1 | mRNA destabilization |
| Q6ZN18 | AEBP1 | Adipocyte enhancer-binding protein 1 | involved in adipogenesis and regulation of gene expression |
| Q9HAW4 | WWTR1 | WW domain-containing transcription regulator protein 1 | cellular proliferation and tissue development |
| Q8N0X4 | PHYHD1 | Phytanoyl-CoA dioxygenase domain-containing protein 1 | metabolism of phytanic acid |
| Q8NCE0 | RASL12 | Ras-like protein family member 12 | cytoskeletal organization, and membrane trafficking |
| Q92997 | DST | Dystonin | plays a role in cytoskeletal organization and cell adhesion |
| Q13619 | CUL4A | Cullin-4A | part of the E3 ubiquitin ligase complex involved in protein degradation and cell cycle regulation |
| Q8NBJ5 | ADAMTSL3 | ADAMTS-like protein 3 | extracellular matrix organization and tissue development |
| P22003 | LTBP1 | Latent transforming growth factor-beta-binding protein 1 | regulating the bioavailability and activation of TGF-beta |
| Q8TDX7 | NKTR | Natriuretic peptide receptor | involved in the regulation of blood pressure and fluid balance |
| Q15389 | ANGPT1 | Angiopoietin-1 | plays a role in angiogenesis and vascular development |