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. 2024 Jan 30;11:1324636. doi: 10.3389/fpubh.2023.1324636

Table 3.

Symptoms, health status, activity level, and missed work over time among adult INSPIRE SARS-CoV-2-positive participants by ethnicity and race.

Enrollmenta 3-Montha 6-Monthb
Ethnicity Race Ethnicity Race Ethnicity Race
Hispanic
(N = 330)
Non-Hispanic (N = 2,024) Asian
(N = 258)
Black
(N = 186)
Other/ Multiple
(N = 232)
White
(N = 1,665)
Hispanic
(N = 330)
Non-Hispanic
(N = 2,024)
Asian
(N = 258)
Black
(N = 186)
Other/ Multiple
(N = 232)
White
(N = 1,665)
Hispanic
(N = 174)
Non-Hispanic (N = 1,208) Asian
(N = 142)
Black
(N = 109)
Other/ Multiple
(N = 124)
White
(N = 1,000)
Symptom category N (%) N (%) N (%) N (%) N (%) N (%) N (%) N (%) N (%) N (%) N (%) N (%) N (%) N (%) N (%) N (%) N (%) N (%)
Constitutional
Tired 257 (78.4) 1,641 (81.7) 204 (79.1) 127 (69.8) 196 (85.6) 1,365 (82.6) 69 (20.9) 465 (23.1) 43 (16.9) 44 (23.8) 69 (29.9) 379 (22.9) 32 (18.7) 241 (20.1) 22 (15.7) 20 (18.7) 30 (24.4) 198 (19.9)
Chills 173 (52.7) 1,013 (50.4) 138 (53.5) 100 (54.9) 126 (55.0) 809 (48.9) 31 (9.4) 115 (5.7) 11 (4.3) 20 (10.8) 18 (7.8) 97 (5.9) 8 (4.7) 54 (4.5) 6 (4.3) 5 (4.7) 3 (2.4) 47 (4.7)
Feeling hot 159 (48.5) 941 (46.9) 113 (43.8) 81 (44.5) 130 (56.8) 767 (46.4) 22 (6.7) 106 (5.3) 11 (4.3) 14 (7.6) 19 (8.2) 85 (5.1) 7 (4.1) 53 (4.4) 8 (5.7) 4 (3.7) 3 (2.4) 46 (4.6)
Fever 105 (32.0) 613 (30.5) 90 (34.9) 54 (29.7) 66 (28.8) 505 (30.6) 15 (4.5) 61 (3.0) 6 (2.4) 9 (4.9) 11 (4.8) 51 (3.1) 2 (1.2) 27 (2.3) 4 (2.9) 3 (2.8) 2 (1.6) 19 (1.9)
Shakes 65 (19.8) 288 (14.3) 32 (12.4) 43 (23.6) 49 (21.4) 226 (13.7) 13 (3.9) 40 (2.0) 7 (2.7) 9 (4.9) 5 (2.2) 32 (1.9) 2 (1.2) 17 (1.4) 4 (2.9) 1 (0.9) 1 (0.8) 12 (1.2)
HEENT c
Headache 217 (66.2) 1,334 (66.4) 165 (64.0) 114 (62.6) 153 (66.8) 1,109 (67.1) 67 (20.3) 265 (13.2) 25 (9.8) 32 (17.3) 44 (19.0) 235 (14.2) 27 (15.8) 131 (10.9) 13 (9.3) 16 (15.0) 15 (12.2) 115 (11.6)
Runny nose 196 (59.8) 1,407 (70.1) 180 (69.8) 93 (51.1) 148 (64.6) 1,174 (71.0) 36 (10.9) 193 (9.6) 20 (7.8) 20 (10.8) 28 (12.1) 160 (9.7) 11 (6.4) 114 (9.5) 13 (9.3) 9 (8.4) 12 (9.8) 91 (9.2)
Loss of smell 147 (44.8) 975 (48.6) 117 (45.3) 80 (44.0) 116 (50.7) 798 (48.3) 45 (13.6) 267 (13.3) 26 (10.2) 22 (11.9) 30 (13.0) 232 (14.0) 13 (7.6) 126 (10.5) 15 (10.7) 8 (7.5) 7 (5.7) 108 (10.9)
Loss of taste 133 (40.5) 895 (44.6) 103 (39.9) 75 (41.2) 111 (48.5) 733 (44.3) 36 (10.9) 215 (10.7) 22 (8.6) 21 (11.4) 27 (11.7) 177 (10.7) 7 (4.1) 100 (8.3) 8 (5.7) 7 (6.5) 2 (1.6) 91 (9.2)
Sore throat 180 (54.9) 1,142 (56.9) 188 (72.9) 80 (44.0) 123 (53.7) 927 (56.1) 33 (10.0) 149 (7.4) 26 (10.2) 16 (8.6) 27 (11.7) 114 (6.9) 11 (6.4) 74 (6.2) 9 (6.4) 6 (5.6) 7 (5.7) 63 (6.3)
Loss of hair 20 (6.1) 70 (3.5) 9 (3.5) 8 (4.4) 9 (3.9) 61 (3.7) 34 (10.3) 114 (5.7) 15 (5.9) 15 (8.1) 16 (6.9) 99 (6.0) 14 (8.2) 68 (5.7) 7 (5.0) 8 (7.5) 9 (7.3) 56 (5.6)
Pulmonary
Cough 188 (57.3) 1,266 (63.0) 165 (64.0) 96 (52.7) 135 (59.0) 1,053 (63.7) 25 (7.6) 145 (7.2) 22 (8.6) 20 (10.8) 23 (10.0) 109 (6.6) 7 (4.1) 64 (5.3) 9 (6.4) 6 (5.6) 5 (4.1) 52 (5.2)
Shortness of breath 110 (33.5) 591 (29.4) 56 (21.7) 69 (37.9) 84 (36.7) 486 (29.4) 34 (10.3) 182 (9.0) 6 (2.4) 23 (12.4) 36 (15.6) 150 (9.0) 16 (9.4) 89 (7.4) 5 (3.6) 10 (9.3) 14 (11.4) 75 (7.5)
Wheezing 37 (11.3) 217 (10.8) 20 (7.8) 26 (14.3) 39 (17.0) 168 (10.2) 8 (2.4) 54 (2.7) 5 (2.0) 4 (2.2) 15 (6.5) 39 (2.4) 5 (2.9) 29 (2.4) 1 (0.7) 3 (2.8) 6 (4.9) 23 (2.3)
Cardiovascular
Chest pains 79 (24.1) 487 (24.3) 40 (15.5) 55 (30.2) 68 (29.7) 400 (24.2) 20 (6.1) 105 (5.2) 9 (3.5) 12 (6.5) 15 (6.5) 88 (5.3) 6 (3.5) 49 (4.1) 6 (4.3) 5 (4.7) 6 (4.9) 41 (4.1)
Palpitations 33 (10.1) 158 (7.9) 12 (4.7) 12 (6.6) 28 (12.2) 138 (8.3) 18 (5.5) 69 (3.4) 6 (2.4) 9 (4.9) 11 (4.8) 61 (3.7) 11 (6.4) 38 (3.2) 1 (0.7) 4 (3.7) 8 (6.5) 34 (3.4)
Gastrointestinal
Diarrhea 88 (26.8) 429 (21.4) 44 (17.1) 54 (29.7) 65 (28.4) 353 (21.4) 17 (5.2) 60 (3.0) 5 (2.0) 6 (3.2) 7 (3.0) 60 (3.6) 5 (2.9) 32 (2.7) 5 (3.6) 2 (1.9) 3 (2.4) 28 (2.8)
Nausea or vomiting 79 (24.1) 347 (17.3) 36 (14.0) 42 (23.1) 59 (25.8) 292 (17.7) 13 (3.9) 59 (2.9) 7 (2.7) 6 (3.2) 9 (3.9) 51 (3.1) 8 (4.7) 34 (2.8) 2 (1.4) 5 (4.7) 4 (3.3) 31 (3.1)
Abdominal pain 44 (13.4) 214 (10.7) 20 (7.8) 28 (15.4) 38 (16.6) 171 (10.3) 10 (3.0) 43 (2.1) 5 (2.0) 4 (2.2) 6 (2.6) 39 (2.4) 12 (7.0) 31 (2.6) 1 (0.7) 2 (1.9) 4 (3.3) 35 (3.5)
Musculoskeletal
Aches 189 (57.6) 1,163 (57.9) 155 (60.1) 107 (58.8) 140 (61.1) 938 (56.7) 48 (14.5) 249 (12.4) 20 (7.8) 33 (17.8) 43 (18.6) 200 (12.1) 22 (12.9) 139 (11.6) 13 (9.3) 18 (16.8) 14 (11.4) 116 (11.7)
Joint pains 106 (32.3) 567 (28.2) 51 (19.8) 55 (30.2) 73 (31.9) 486 (29.4) 40 (12.1) 221 (11.0) 23 (9.0) 32 (17.3) 32 (13.9) 172 (10.4) 15 (8.8) 131 (10.9) 5 (3.6) 15 (14.0) 15 (12.2) 112 (11.3)
Symptom summary
Other symptoms 42 (12.8) 281 (14.0) 21 (8.1) 15 (8.2) 44 (19.2) 242 (14.6) 13 (3.9) 91 (4.5) 6 (2.4) 4 (2.2) 14 (6.1) 82 (4.9) 10 (5.8) 49 (4.1) 3 (2.1) 3 (2.8) 4 (3.3) 50 (5.0)
≥3 symptoms (not including others) 293 (89.3) 1845 (91.9) 241 (93.4) 150 (82.4) 204 (89.1) 1,528 (92.4) 82 (24.8) 430 (21.4) 39 (15.3) 54 (29.2) 63 (27.3) 341 (20.6) 38 (22.2) 225 (18.8) 19 (13.6) 27 (25.2) 26 (21.1) 192 (19.3)
No symptoms 7 (2.1) 26 (1.3) 0 (0.0) 6 (3.3) 5 (2.2) 22 (1.3) 172 (52.1) 1,148 (57.1) 165 (64.7) 99 (53.5) 115 (49.8) 929 (56.0) 97 (56.7) 714 (59.5) 90 (64.3) 62 (57.9) 64 (52.0) 590 (59.4)
Health status
Excellent 26 (8.0) 212 (10.6) 29 (11.4) 20 (10.9) 21 (9.2) 167 (10.2) 17 (9.9) 137 (11.4) 17 (12.1) 10 (9.3) 11 (8.9) 113 (11.4)
Very good 78 (24.0) 559 (28.0) 56 (22.0) 31 (16.8) 47 (20.6) 500 (30.4) 49 (28.5) 354 (29.4) 43 (30.5) 21 (19.4) 32 (25.8) 310 (31.2)
Good 102 (31.4) 746 (37.3) 103 (40.6) 67 (36.4) 68 (29.8) 607 (36.9) 54 (31.4) 399 (33.2) 37 (26.2) 37 (34.3) 33 (26.6) 340 (34.2)
Fair 86 (26.5) 380 (19.0) 57 (22.4) 47 (25.5) 66 (28.9) 290 (17.6) 33 (19.2) 257 (21.4) 40 (28.4) 27 (25.0) 34 (27.4) 187 (18.8)
Poor 29 (8.9) 92 (4.6) 8 (3.1) 17 (9.2) 23 (10.1) 73 (4.4) 17 (9.9) 46 (3.8) 4 (2.9) 8 (7.4) 12 (9.7) 39 (3.9)
Do not know 4 (1.2) 7 (0.3) 1 (0.4) 0 (0.0) 2 (0.9) 8 (0.5) 2 (1.2) 9 (0.7) 0 (0.0) 4 (3.7) 2 (1.6) 6 (0.6)
No answer 0 (0.0) 3 (0.1) 0 (0.0) 2 (1.1) 1 (0.4) 0 (0.0) 0 (0.0) 1 (0.1) 0 (0.0) 1 (0.9) 0 (0.0) 0 (0.0)
Activity leveld
Same as before 191 (58.8) 1,349 (67.5) 192 (75.6) 100 (54.3) 125 (54.8) 1,114 (67.8) 109 (63.4) 822 (68.3) 105 (74.5) 64 (59.3) 74 (59.7) 678 (68.1)
Somewhat less than before 99 (30.5) 502 (25.1) 53 (20.9) 61 (33.2) 76 (33.3) 404 (24.6) 45 (26.2) 286 (23.8) 32 (22.7) 25.9 (28) 34 (27.4) 239 (24.0)
Much less than before 35 (10.8) 147 (7.4) 9 (3.5) 23 (12.5) 27 (11.8) 126 (7.7) 18 (10.5) 95 (7.9) 4 (2.8) 14.8 (16) 16 (12.9) 78 (7.8)
Missed work due to health reasons past 3 months
0–5 workdays 213 (65.5) 1,376 (68.9) 198 (78.0) 99 (53.8) 140 (61.4) 1,147 (69.8) 119 (69.2) 889 (73.9) 114 (80.9) 60 (55.6) 78 (62.9) 752 (75.6)
6–10 workdays 30 (9.2) 156 (7.8) 12 (4.7) 26 (14.1) 19 (8.3) 125 (7.6) 11 (6.4) 70 (5.8) 8 (5.7) 12 (11.1) 10 (8.1) 50 (5.0)
11–20 workdays 16 (4.9) 79 (4.0) 7 (2.8) 10 (5.4) 12 (5.3) 65 (4.0) 9 (5.2) 34 (2.8) 2 (1.4) 10 (9.3) 9 (7.3) 20 (2.0)
Up to 4 weeks 16 (4.9) 58 (2.9) 9 (3.5) 16 (8.7) 15 (6.6) 34 (2.1) 6 (3.5) 23 (1.9) 3 (2.1) 5 (4.6) 5 (4.0) 15 (1.5)
Do not work 50 (15.4) 328 (16.4) 28 (11.0) 33 (17.9) 42 (18.4) 272 (16.6) 27 (15.7) 187 (15.5) 14 (9.9) 21 (19.4) 22 (17.7) 158 (15.9)

aIncluded COVID-19-positive participants who completed both enrollment and 3-month surveys; excluded participants with missing ethnicity (n = 48) and with missing symptom responses (n = 18 for enrollment survey; n = 12 for 3-month survey); excluded participants with missing race (n = 61) and missing symptom responses (n = 19 for enrollment survey; n = 12 for 3-month survey). bIncluded COVID-19-positive participants who completed enrollment, 3-month, and 6-month surveys; excluded participants with missing ethnicity (n = 23) and with missing symptom responses (n = 11); excluded participants with missing race (n = 30) and with missing symptom responses (n = 11). cHEENT = head, ears, eyes, nose, throat. dExcluded participants with missing health status (n = 30 for 3-month survey; n = 7 for 6-month survey), or activity level (n = 31 for 3-month survey; n = 7 for 6-month survey), or missed work variable (n = 32 for 3-month survey; n = 7 for 6-month survey).