Figure 3.

Description of the preclinical research published from their inception to February 13, 2023. Most of the original papers were about CAR cells to treat viral infection, focusing on HIV viruses and using CAR T cells. (A) Distribution of Infection Types: Out of the original papers, 67 focused on viral infections, while four centered on fungal infections. (B) Distribution of Viral Infections: The predominant CAR designs targeted HIV-infected cells. (C) Distribution of CAR-expressing Cell Types: T cells were the most commonly employed cells for expressing CAR constructs.