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CAR cells targeting HIV-infected cells. Cytotoxic cells are redirected against HIV-infected cells by the expression of gp-120-specific CARs on their surface. Two main structures have been used. The extracellular domain of CD4 receptors and broadly neutralising scFv antibodies. Both target the gp-120 and could successfully kill HIV-infected cells and control HIV infection. Figures created using BioRender.com.
