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. 2024 Feb 2;121(6):e2300644120. doi: 10.1073/pnas.2300644120

Fig. 4.

Fig. 4.

xenoAMP(ORF1ab)-dsRNA complex activate inflammation in C57BL/6 mice. C57BL/6 mice is either untreated or injected with xenoAMP(ORF1ab), poly(I:C) or xenoAMP(ORF1ab)-poly(I:C) complex. Samples are collected after 2 h. (A) Concentration of CXCL1 and IL-6 in the plasma. (B) Concentration of CXCL1 and IL-6 in the lung (n = 5). (C) WBC, neutrophil, lymphocyte and monocyte count in the peripheral blood (n = 10). All the data is presented as mean ± SD. The statistical test of the hematology data and lung cytokine data are performed with unpaired two-tailed t test, while the plasma cytokine data is analyzed with one-way ANOVA (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001).