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Comparison of WT and variant Fn3-3 (left) and Fn3-56 (right) domain crystal structures. A: cartoon representation of aligned WT and variant domain structures, with mutated residue sidechains shown in stick representation. B: detail of region surrounding mutated residue. Sidechains shown in stick representation. C and D: detail of electron density surrounding WT (C) residue mutated in variant structure (D). 2Fo-Fc maps displayed at sigma = 1.0.
