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. 2024 Feb 10;14(2):e080334. doi: 10.1136/bmjopen-2023-080334

Table 1.

Top 10 most used measures for brain health measurements

Measurement method Category Number of studies using this method (%)
Grey matter volume in specific region(s) Imaging 133 (18.3)
White matter hyperintensities Imaging 133 (18.3)
Total brain volume Imaging 132 (18.2)
Whole brain grey matter volume Imaging 106 (14.6)
Hippocampal volume Imaging 105 (14.4)
Fractional anisotropy Imaging 102 (14.0)
White matter volume in specific region(s) Imaging 95 (13.1)
Trail making test A and/or B Cognitive testing 86 (11.8)
Whole brain white matter volume Imaging 77 (10.6)
Mini-Mental Status Examination Cognitive testing 73 (10.0)

Row data are not mutually exclusive as many studies used more than one category of methods.