Table 1.
Measurement method | Category | Number of studies using this method (%) |
Grey matter volume in specific region(s) | Imaging | 133 (18.3) |
White matter hyperintensities | Imaging | 133 (18.3) |
Total brain volume | Imaging | 132 (18.2) |
Whole brain grey matter volume | Imaging | 106 (14.6) |
Hippocampal volume | Imaging | 105 (14.4) |
Fractional anisotropy | Imaging | 102 (14.0) |
White matter volume in specific region(s) | Imaging | 95 (13.1) |
Trail making test A and/or B | Cognitive testing | 86 (11.8) |
Whole brain white matter volume | Imaging | 77 (10.6) |
Mini-Mental Status Examination | Cognitive testing | 73 (10.0) |
Row data are not mutually exclusive as many studies used more than one category of methods.