Table 4.

Changes in relative abundance of microbes in chronic pain patients compared to controls at phylum, family, genus and species level.

	Migraine	ME/CFS	FM	Axial spondy-oarthritis	Bladder pain syndrome	Gulf-war	CRPS	Chronic angina
Phylum level
Actinobacteria	Higher P (29)	Higher C (46)	Higher C (33)
Bacteroidetes	Higher P (29)	Higher P (46) Higher P (40)	Higher P (33) Higher C (33)
Firmicutes	Higher C (29) Higher P (29) Higher P (32)	Higher C (46) Higher C (35) Higher C (40)	Higher P (33) Higher C (33)				Higher C (44)	Higher C (49)
Proteobacteria	Higher P (29)	Higher C (35)					Higher P (44)	Higher P (49)
Ascomycota		Higher C (41)
Basidiomycota		Higher P (41)
Stramenopiles		Higher P (41)
Zygomycota		Higher P (41)
Family level
Bacteroidaceae		Higher C (35) Higher P (40)	Higher C (33)
Barnesiellaceae		Higher P (40)
Bifidobacteriaceae		Higher C (35)	Higher C (33)
Christensenellaceae	Higher C (29)
Clostridiaceae		Higher P (43)
Erysipelotrichaceae	Higher P (29)		Higher C (33)
Enterobacteriaceae		Higher P (35)
Eubacteriaceae	Higher P (48)
Lachnospiraceae	Higher P (29) Higher C (29)	Higher C (43) Higher C (40)	Higher C (33)			Higher C (37)
Peptoniphilaceae	Higher P (48)
Porphyromonadaceae		Higher C (43)
Prevotellaceae		Higher P (35)
Rikenellaceae		Higher C (35)	Higher P (33)
Ruminococcaceae	Higher C (29)	Higher C (35)
Genus level
Agathobacter	Higher C (48)
Alistipes		Higher P (34)	Higher P (33)
Anaerostipes	Higher C (29)	Higher C (40)						Higher P (49)
Anaerotruncus	Higher P (29)	Higher P (35)
Asaccharobacter		Higher C (34)
Bacteroides	Higher P (29)	Higher P (40)	Higher C (33)
Bifidobacterium		Higher C (35)	Higher C (33)
Blautia		Higher P (38)
Butyricicoccus	Higher P (29)
Catenibacterium	Higher C (48)
Clostridium	Higher P (48)	Higher P (43)	Higher C (33)
Collinsella		Higher C (38)
Coprobacillus	Higher P (29)	Higher P (43) Higher P (38)
Coprococcus		Higher C (43) Higher P (35)
Dialister		Higher C (34)				Higher C (37)
Dorea	Higher C (48) Higher P (29)	Higher C (43)	Higher P (33)
Eggerthella	Higher P (29) Higher P (48)	Higher P (38) Higher P (35)
Erysipelatoclostridium								Higher P (49)
Eubacterium	Higher C (48) Higher P (29)		Higher C (33)
Faecalibacterium	Higher C (48) Higher C (32)	Higher C (43) Higher C (38) Higher C (35)						Higher C (49)
Frisingicoccus	Higher C (48)
Fusicantenibacter	Higher C (48)
Holdemanella	Higher C (48)							Higher P (49)
Holdemania		Higher C (34)
Hungatella	Higher P (48)
Lachnospira	Higher P (29) Higher C (48)	Higher C (38)
Lachnospiraceae_uc	Higher C (48)
Lactococcus		Higher P (35)
Lactonifactor		Higher P (34)
Longicatena	Higher P (48)
Odoribacter	Higher P (29)	Higher C (43)
Olsenella	Higher P (48)
Oribacterium	Higher C (29)
Oscillospira		Higher P (35)
PAC000195_g	Higher C (48)
PAC000692_g	Higher C (48)
PAC001134_g	Higher C (48)
PAC001137_g	Higher C (48)
Parabacteroides	Higher P (29)
Phascolarctobacterium		Higher P (40)
Romboutsia								Higher C (49)
Roseburia	Higher C (48)	Higher C (43) Higher C (34)	Higher P (33)
Ruminococcus						Higher P (37)
Sarcina								Higher P (49)
SMB53	Higher P (29)
Streptococcus								Higher P (49)
Subdoligranulum								Higher C (49)
Sutterella	Higher P (29)
Syntrophococcus		Higher C (34)
Varibaculum	Higher P (29)
Veillonella	Higher P (29)
Weissella								Higher P (49)
Species level
Alceligenes spp	Higher P (39)
B. Uniformis			Higher C (42)
Bacteroides clarus	Higher C (32)
Bacteroides dorei				Higher C (30)
Bacteroides intestinalis	Higher C (32)
Bacteroides ovatus		Higher P (40)
Bacteroides salyersiae	Higher C (32)
Bacteroides stercoris	Higher C (32)
Bacteroides uniformis		Higher P (40)
Bifidobacterium adolescentis	Higher C (32)			Higher P (30)
Blastocystis		Higher P (41)
Blauti sp. N6H1.15		Higher P (36)
Blautia hydrogenotrophica	Higher P (32)
Butyricoccus desmolans			Higher P (42)
Butyrivibrio crossotus	Higher C (32)
C. aerofaciens					Higher C (31)
C. bolteae		Higher P (36)
C. scindens		Higher P (36)
C. secundus		Higher C (36)
Clostridium asparagiforme	Higher P (32)	Higher P (43)
Clostridium bolteae	Higher P (32)
Clostridium citroniae	Higher P (32)
Clostridium clostridioforme	Higher P (32)
Clostridium coccoides	Higher P (39)
Clostridium hathewayi	Higher P (32)
Clostridium propionicum	Higher P (39)
Clostridium ramosum	Higher P (32)
Clostridium sp. L2_50	Higher C (32)
Clostridium spiroforme	Higher P (32)
Clostridium symbiosum	Higher P (32)	Higher P (43)
Coprobacillus bacterium		Higher P (43)
Coprococcus catus	Higher C (32)	Higher C (43)
Dorea formicigenerans		Higher C (43)
Dorea longicatena		Higher C (43)
E. coli		Higher C (45)
E. faecalis		Higher P (45)
E. ramosum		Higher P (36)
E. rectale		Higher C (36)
E. sinensis					Higher C (31)
Eggerthella lenta	Higher P (32) Higher P (39)
Eisenber giella tayi			Higher P (42)
Eisenbergiella massiliensis			Higher P (42)
Eubacterium hallii	Higher C (32)
Eubacterium ramulus	Higher C (32)
Faecalibacterium cf.		Higher C (43)
Faecalibacterium prausnitzii	Higher C (32)	Higher C (36) Higher C (43)	Higher C (42)		Higher C (31)
Flavonifractor plautii	Higher P (32)		Higher P (42)
Herpes simplex	Higher P (39)
Intestinimonas butyricipro ducens			Higher P (42)
L. longoviformis					Higher C (31)
Lachnoclostridium sp. YL32		Higher P (36)
Lachnospiraceae bacterium	Higher P (32)
Methanobrevibacter smithii	Higher C (32)
Micromycetes spp (campesterol and sitosterol)	Higher P (39)
Odoribacter splanchnicus	Higher C (32)	Higher C (43)			Higher C (31)
Parabacteroides merdae		Higher C (43)
Peptostreptococcaceae	Higher C (32)
Porphyromonas bennonis				Higher P (30)
Prevotella copri	Higher C (32)
Pseudonocardia spp	Higher P (39)
R. gnavus		Higher P (36)
R. lactatiformans		Higher P (36)
Rhodococcus spp	Higher P (39)
Roseburia inulinivorans		Higher C (43)
Ruminococcus callidus	Higher C (32)
Ruminococcus champanellensis	Higher C (32)
Ruminococcus gnavus	Higher P (32)
Ruminococcus obeum	Higher C (32)	Higher C (43)
S. intestinalis		Higher P (36)
S. sanguinis		Higher P (45)
Streptococcus anginosus				Higher C (30)
Sutterella wadsworthensis	Higher C (32)
T. nexilis		Higher P (36)

C, controls; P, patients.