Table-I.

Baseline demographics and scores of responders and non-responders.

	Responders (n=26)	Non-responders (n=4)
Gender
Male	15 (57.7%)	2 (50%)
Female	11 (42.3%)	2 (50%)
Age
20-40 years	17 (65.4%)	1 (25%)
41-60 years	6 (23.1%)	3 (75%)
61-80 years	3 (11.5%)	0 (0%)
Weight
40-60 kgs	7 (26.9%)	1 (25%)
61-80 kgs	13 (50%)	1 (25%)
81-90 kgs	5 (19.2%)	2 (50%)
Above 100 kgs	1 (3.8%)	0 (0%)
BMI
Underweight	2 (7.7%)	1 (25%)
Healthy	10 (38.5%)	0 (0%)
Overweight	11 (42.3%)	3 (75%)
Obese	3 (11.5%)	0 (0%)
IBS sub-type
Diarrhea-predominant	8 (30.8%)	1 (25%)
Constipation-predominant	14 (53.8%)	2 (50%)
Mixed-type	4 (15.4%)	1 (25%)
Treatment Naive	16 (61.5%)	2 (50%)
Treatment experienced	10 (38.5%)	2 (50%)
Scores adjusted to a range 0-100
Pain/discomfort score
W0	64.83±1.81	57.14±5.83
W1	32.97±1.73	46.43±3.57
W2	24.72±1.49	39.29±3.57
W3	19.23±1.36	39.29±3.57
W4	18.13±1.27	37.71±4.12
Total IBS-QOL
W0	22.20±1.31	40.81±3.29
W4	58.40±2.37	56.07±3.86
Dysphoria
W0	25.36±1.74	47.66±5.00
W4	62.50±3.29	60.16±3.69
Interference with activity
W0	21.29±1.51	41.07±3.09
W4	57.28±2.85	52.68±3.38
Body image
W0	19.95±2.02	35.94±5.34
W4	54.33±2.90	53.12±10.97
Health worry
W0	22.76±1.64	43.75±8.59
W4	58.97±2.65	60.42±9.24
Food avoidance
W0	26.60±1.96	39.58±7.12
W4	73.40±4.06	54.17±11.02
Social reaction
W0	22.60±1.77	35.94±2.99
W4	57.69±3.47	59.37±4.03
Sexual function
W0	11.54±2.39	37.50±5.10
W4	42.31±4.76	56.25±6.25
Relationship
W0	20.51±2.37	35.42±6.25
W4	51.60±3.76	50.00±3.40

Values are n (%) or mean ± standard error of mean; W: Week.