Figure 3: Heatmap of potentially targetable TFs to reduce oncogene expression.

Heatmap of prognostic scores for TFs that bind to oncogene promoters. TFs are classified as potential activators, bifunctional, or repressors based on annotated effector domains in TFRegDB. Oncogenes that contribute to cancer development through amplifications (A), fusions (F), or mutations (M) are indicated next to the gene name. Oncogenes indicated in magenta have at least one TF that is activator/bifunctional with a prognosis score > 0.33.