Figure 3. Molecular histology of fallopian fimbriae.
(A) A wild-type mouse at 12mo of age shows little p53 or MYC staining in fallopian tube epithelium (FTE). (B) OvTrpMyc fallopian tube (FT) at 15mo of age, F135, exhibiting p53 and MYC staining within FTE. (C) Intra-abdominal tumor dissected from an OvTrpMyc mouse with positive PAX8, p53, and MYC staining. (D) An ovarian fat pad metastatic nodule. (E) OvTrpMyc mouse at 12mo of age, with vacuolated fallopian fimbriae positive for p53 and MYC.