Table 1: Mixed-effects model identifies strong effects of anatomical features on single-voxel fMRI responses.

Weight estimates for delay, amplitude and specificity, for different stimulus frequencies as a function of cortical depth, position in V1, vascular compartment. Values in brackets represent 95% CI. (All temporal specificity values and gradients are multiplied by 100 for clarity.)

Effect of anatomical correlates on response onset delay with respect to stimulus presentation
Frequency	Delay at WM (ms)	WM → CSF (ms/mm)	Anterior → Posterior (ms/mm)	Impact of vein (ms)
0.05 Hz	3110 [2740, 3470]	179 [123, 236]	42 [28, 57]	238 [206, 269]
0.10 Hz	3300 [2670, 3010]	178 [127, 230]	42 [33, 52]	208 [181, 236]
0.20 Hz	2840 [2670, 3010]	156 [103, 209]	22 [15, 30]	204 [182, 227]
Effect of anatomical correlates on signal amplitude
Frequency	Amplitude at WM (%)	WM → CSF (%/mm)	Anterior → Posterior (%/mm)	Impact of vein (%)
0.05 Hz	4.38 [3.76, 5.00]	0.77 [0.37, 1.18]	0.04 [0.02, 0.07]	6.99 [6.88, 7.10]
0.10 Hz	2.42 [2.00, 2.83]	0.45 [0.27, 0.61]	0.00 [−0.01, 0.01]	3.74 [3.68, 3.81]
0.20 Hz	0.74 [0.62, 0.86]	0.14 [0.07, 0.22]	−0.007 [−0.012, −0.001]	1.19 [1.16, 1.21]
Effect of anatomical correlates on temporal specificity (multiplied by 100)
Frequency	100 × specificity at WM	WM → CSF (mm−1)	Anterior → Posterior (mm−1)	Impact of vein
0.10 Hz	55.07 [50.96,59.33]	1.04 [0.05, 2.05]	−0.44 [−0.27, −0.62]	−1.06 [−1.61, −0.50]
0.20 Hz	16.88 [15.29,18.52]	0.39 [−0.06, 0.86]	−0.25 [−0.34, −0.17]	−0.12 [−0.34, 0.11]