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. 2024 Feb 13;57:6. doi: 10.1186/s40659-024-00484-3

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 7 — Effect of eMSC on inflammatory factors and the fertility restoration in the mouse endometrium. Relative gene expression of (A)Ifng, (B)Il-2, (C)Tnfa, (D)Il-10 and (E)Il-4 in the PBS group (blue bars) and the eMSC group (yellow bars) at different post-operative timepoints (n = 4). The injured uterine horn (L) was normalized against the control uterine horn (R) from the same animal. (F) Images showing the uterine horns with the number of implantation sites (blue arrow) in (I and II) non-injury group, (III and IV) injured endometrium with PBS transplantation and (V and VI) injured endometrium with eMSC-transplantation. (G) Number of implantation sites on the control side (blue bars) and injured side (yellow bars) of the uterine horn (n = 4). Results are presented as mean ± SD, *P < 0.05. Abbreviations: eMSC, endometrial mesenchymal stem-like cells; Ifn, interferon; Il, interleukin; IS, implantation sites; Tnf, tumor necrosis factor