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. 2024 Feb 13;22:148. doi: 10.1186/s12967-024-04913-5

Table 1.

Correlation between SAE1 protein expression and clinicopathologic characteristics of GC

Parameter Total (n = 93) SAE1 expression level P Value
High
n = 65
Low
n = 28
Age (years)
  ≥ 60 67 45 22 0.357
  < 60 26 20 6 -
Gender
 Male 59 43 16 0.408
 Female 34 22 12
Tumor size
  ≥ 5 60 42 18 0.976
  < 5 33 23 10
Pathological type
 Infiltrating 54 39 15 0.865
 Elevated 7 5 2
 Ulcerative 30 20 10
Grade
 I-II 40 32 8 0.065
 III 53 33 20
TNM stage
 I-II 35 20 15 0.029*
 III-IV 56 44 12
Vascular invasion
 No 65 41 24 0.029*
 Yes 28 24 4
Nerve invasion
 No 79 53 26 0.215
 Yes 14 12 2
Overall survival
 Survive 33 12 21 0.013*
 Die 60 37 23

High and low expression was determined as total immunohistochemistry scores of 0–3 and 3–12 respectively

*P < 0.05 was identified as statistically significant