Table 2.
Predictors of CIN1 + recurrent or residual disease
| Total | Event (%) | Univariate HR | Multivariate analysis | |||
|---|---|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |||
| Age | ||||||
| ≤ 40 | 154 | 16 (10.39) | 1 | |||
| > 40 | 231 | 36 (15.58) | 1.570 (0.870–2.835) | 0.134 | ||
| Menopause | ||||||
| No | 292 | 33 (11.3) | 1 | |||
| Yes | 93 | 19 (20.43) | 1.992 (1.129–3.515) | 0.017 | ||
| Parity | ||||||
| 0 | 74 | 8 (10.81) | 1 | 0.069 | ||
| 1 | 75 | 4 (5.33) | 0.463 (0.139–1.536) | 0.208 | ||
| ≥ 2 | 236 | 40 (16.95) | 1.468 (0.686–3.144) | 0.323 | ||
| Final Diagnosis | ||||||
| Chronic cervicitis | 19 | 3 (15.79) | 1 | 0.973 | ||
| LSIL | 20 | 2 (10) | 0.843 (0.140–5.069) | 0.852 | ||
| HSIL | 346 | 47 (13.58) | 0.998 (0.310–3.218) | 0.998 | ||
| Margin | ||||||
| Negative | 339 | 40 (11.8) | 1 | 1 | ||
| Positive | 46 | 12 (26.09) | 1.952 (1.020–3.735) | 0.043 | 1.948 (1.020–3.720) | 0.043 |
| Exo (+) | 9 | 3 (33.33) | 2.782 (0.859–9.008) | 0.088 | ||
| Endo (+) | 32 | 9 (28.13) | 2.061 (0.993–4.277) | 0.052 | ||
| Both (+) | 5 | 0 (0) | 0.000 (0.000–0.000) | 0.987 | ||
| HPV status after LEEP | ||||||
| Negative | 267 | 13 (4.87) | 1 | 1 | ||
| Positive | 118 | 39 (33.05) | 6.843 (3.650-12.827) | 0.000 | 6.848 (3.652–12.840) | 0.000 |