Table 2.

Gene transcripts normalized by DMF in CUS-exposed male rats (absolute ΔLogFC > 0.3)

GENE	CUS RESPONSE	Encoded protein function
Nnat	↑	Neuronatin; ER membrane protein and linked to ER stress; involved in inflammation, calcium signalling, and glucose signalling
Tacr3	↑	Tachykinin/neurokinin 3 receptor; promotes acetylcholine release; involved in learning and memory, implicated in anxiety and depression
Arhgdib	↑	Rho GDP dissociation inhibitor beta; involved in immune and inflammatory responses
Lyz2	↑	Lysozyme 2; marker of microglial activation; linked to immune and inflammatory responses
Gpx3	↑	Glutathione peroxidase 3; known target gene of Nrf2; selenoprotein of the glutathione peroxidase family; antioxidant enzyme
S100a11	↑	Calgizarrin; calcium binding protein; implicated in pro-inflammatory processes
Rpl30	↓	Ribosomal protein L30; component of 60S subunit
Lce1d	↓	Late cornified envelope 1d; known target gene of Nrf2 in keratinocytes; function in brain unknown