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. 2024 Feb 13;21:23. doi: 10.1186/s12984-024-01318-9

Fig. 3.

Fig. 3

Here we use a worked example of multiple sclerosis within the patient-in-the-loop framework to improve mobility. Here musculoskeletal models of gait efficiency and symmetry are used to aid diagnosis, a device is used for intervention, and a musculoskeletal model of human-device interaction is used to predict several gait metrics when using the device. Patient involvement occurs at several points within the loop