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. 2024 Feb 13;21:23. doi: 10.1186/s12984-024-01318-9

Table 4.

Sensory and pain: state-of-the-art and future directions

State-of-the-art a. Separate models for typical development and for specific neurodevelopmental
and neurodegenerative conditions.
b. Experimental paradigms and models that constrain dimensionality.
Future directions a. Multisensory models that consider feedforward and feedback mechanisms.
b. Sensitive and specific diagnostic models that account for general population
variability and phenotypic heterogeneity within conditions.
c. High-dimensional diagnostic and treatment models that account for interplay
between physiological, cognitive, emotional, and behavioral factors to support
optimization and personalization.