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. 2024 Feb 12;46(1):2313182. doi: 10.1080/0886022X.2024.2313182

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© 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 2. — Functional enrichment analysis and pathway of DEGs. (A) KEGG enrichment analysis. (B) KEGG enrichment analysis in the lipid metabolism pathway. (C) PPI network analysis in the AA metabolism pathway. (D) GO enrichment analysis. (E) Bubble plot. (F) RT-PCR detection of ALOX12 mRNA in db/m and db/db mouse models, **p < .01. (G, H) The diagnostic efficacy of ALOX12 for DKD was verified using ROC curves in dataset GSE1009 and dataset GSE7253.