Table 1.
Parameter | NC (n = 6) | MCD (n = 6) | DKD |
p Value | |
---|---|---|---|---|---|
DKD1 (n = 6) | DKD2 (n = 6) | ||||
Age (years) | 48.667 ± 12.307 | 59.000 ± 10.445 | 55.333 ± 12.176 | 54.833 ± 9.109 | .4251 |
Sex (F/M) | 2/4 | 2/4 | 2/4 | 1/5 | .901 |
U-ACR (mg/g) | 11.128 ± 9.740 | 779.170 ± 493.270* | 124.110 ± 91.336 | 3615.100 ± 2278.700*,& | <.01 |
Serum ALOX12 (ng/mL) | 73.403 ± 8.113 | 72.877 ± 11.387 | 92.048 ± 4.799**,# | 111.620 ± 20.224*,# | <.01 |
Urine ALOX12/urine creatinine (ng/mmol) | 338.7 ± 81.44 | 260.2 ± 77.12 | 340.2 ± 132.3 | 604.5 ± 174.5**,###,&& | <.001 |
NC group: the normal patients; MCD group: patients with microscopic renal disease patients; DKD1 group: the diabetic kidney disease patients with UACR <300 mg/g; DKD2 group: the diabetic kidney disease patients with UACR ≥300 mg/g; U-ACR: urine-albumin/urine creatinine ratio.
vs. NC *p < .05, **p < .01; vs. MCD #p < .01, ###p < .001; vs. DKD1 &p < .05; vs. DKD1 &&p < .01.