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. Author manuscript; available in PMC: 2024 Feb 13.
Published in final edited form as: Neuropharmacology. 2020 Jul 29;177:108253. doi: 10.1016/j.neuropharm.2020.108253

Table 2 -.

Statistical analyses of data in Fig. 3: SNI-induced latent sensitization

group Fig. 3 panel n data analyzed time side time x side
control A 8 SNI,
days −4 to 35
p = 0.0026
F(5, 35) = 4.58
p = 0.0017
F(1, 7) = 24
p < 0.0001
F(5, 29) = 8.3
B 8 day 28: vehicle i.th.
then NTX i.th.
p < 0.0001
F(4, 28) = 16
p = 0.0085
F(1, 7) = 13
p = 0.0042
F(4, 28) = 4.8
C 5 day 35:
NTX i.th.
p = 0.0039
F(4, 16) = 6.0
p = 0.063
F(1, 4) = 27
p = 0.403
F(4, 16) = 1.07
RP67580 D 7 SNI,
days −4 to 35
p = 0.0058
F(5, 30) = 4.12
p = 0.0006
F(1, 6) = 42
p < 0.0001
F(5, 30) = 9.4
E 7 day 28: RP67580 i.th.
then NTX i.th.
p = 0.0018
F(4, 24) = 5.9
p = 0.0084
F(1, 6) = 14.9
p = 0.98
F(4, 24) = 0.08
F 7 day 35:
NTX i.th.
p = 0.49
F(4, 24) = 0.88
p = 0.14
F(1, 6) = 2.88
p = 0.52
F(4, 24) =0.82

Data in the panels of Fig. 3 were analyzed by two-way ANOVA, repeated-measures by both variables: time of von Frey measures and side (ipsilateral vs. contralateral). Panel A was analyzed using mixed-effects analysis because a few baseline data were missing. n is the sample size. In row C, 3 of the 8 rats were excluded because they lost the i.th. catheter.