Table 2 -.
Statistical analyses of data in Fig. 3: SNI-induced latent sensitization
| group | Fig. 3 panel | n | data analyzed | time | side | time x side |
|---|---|---|---|---|---|---|
| control | A | 8 | SNI, days −4 to 35 |
p = 0.0026 F(5, 35) = 4.58 |
p = 0.0017 F(1, 7) = 24 |
p < 0.0001 F(5, 29) = 8.3 |
| B | 8 | day 28: vehicle i.th. then NTX i.th. |
p < 0.0001 F(4, 28) = 16 |
p = 0.0085 F(1, 7) = 13 |
p = 0.0042 F(4, 28) = 4.8 |
|
| C | 5 | day 35: NTX i.th. |
p = 0.0039 F(4, 16) = 6.0 |
p = 0.063 F(1, 4) = 27 |
p = 0.403 F(4, 16) = 1.07 |
|
| RP67580 | D | 7 | SNI, days −4 to 35 |
p = 0.0058 F(5, 30) = 4.12 |
p = 0.0006 F(1, 6) = 42 |
p < 0.0001 F(5, 30) = 9.4 |
| E | 7 | day 28: RP67580 i.th. then NTX i.th. |
p = 0.0018 F(4, 24) = 5.9 |
p = 0.0084 F(1, 6) = 14.9 |
p = 0.98 F(4, 24) = 0.08 |
|
| F | 7 | day 35: NTX i.th. |
p = 0.49 F(4, 24) = 0.88 |
p = 0.14 F(1, 6) = 2.88 |
p = 0.52 F(4, 24) =0.82 |
Data in the panels of Fig. 3 were analyzed by two-way ANOVA, repeated-measures by both variables: time of von Frey measures and side (ipsilateral vs. contralateral). Panel A was analyzed using mixed-effects analysis because a few baseline data were missing. n is the sample size. In row C, 3 of the 8 rats were excluded because they lost the i.th. catheter.