Effect of maternal programming in depression-like behavior in inter- and transgenerational inheritance. Seconds of immobility during tail suspension test were measured and compared CAF group from (A) F1, (D) F2, and (G) F3 generations with their respective CON group. The results are expressed as mean ± SEM, followed by ANOVA post hoc Tukey. *p < 0.05 versus control group. Seconds of immobility during FST were measured and compared CAF group from (B) F1, (E) F2, and (H) F3 generations with their respective CON group. The results are expressed as mean ± SEM, followed by ANOVA post hoc Tukey. *p < 0.05 versus control group. Contrarily, time spent swimming during FST was measured and compared CAF group from (C) F1, (F) F2, and (I) F3 generations with their respective CON group. Results are expressed as mean ± SEM, followed by ANOVA post hoc Tukey. *p < 0.05 versus control group. CAF, cafeteria diet group; CON, chow diet group.