Table 7.
Results of two-way ANOVA for prenatal diet and behavioral phenotype group comparison in brain region of F3 corresponding to Figure 6
| Region | Model | Degree of freedom | Sum of squares | Mean square | F value | Adjusted p-value | |
|---|---|---|---|---|---|---|---|
|
AMY Contrast CON-A Vs CAF-A |
AMY ∼ PD * phenotype | PD | 1 | 0.1138 | 0.1138 | 15.067 | 0.0003*** |
| Phenotype | 1 | 0.0000 | 0.0000 | 0.000 | 0.9943 | ||
| PD * phenotype | 1 | 0.0682 | 0.0682 | 9.032 | 0.0041** | ||
|
S1 Contrast CON-A Vs CAF-A |
S1 ∼ PD * phenotype | PD | 1 | 0.0089 | 0.0089 | 5.01 | 0.0297* |
| Phenotype | 1 | 0.0001 | 0.0001 | 0.07 | 0.7921 | ||
| PD * phenotype | 1 | 0.0181 | 0.0181 | 10.15 | 0.0025** | ||
|
3V Contrast CON-NA Vs CAF-A |
3V ∼ PD * phenotype | PD | 1 | 0.1096 | 0.1096 | 26.945 | 0.0001*** |
| Phenotype | 1 | 0.0164 | 0.0164 | 4.050 | 0.0497* | ||
| PD * phenotype | 1 | 0.0127 | 0.0127 | 3.131 | 0.0830 | ||
|
RCx Contrast CON-NA Vs CAF-A |
RCx ∼ PD * phenotype | PD | 1 | 0.0928 | 0.0928 | 15.79 | 0.0002*** |
| Phenotype | 1 | 0.0678 | 0.0678 | 11.54 | 0.0013** | ||
| PD * phenotype | 1 | 0.0891 | 0.0891 | 15.17 | 0.0002*** | ||
|
3V Contrast CON-NA Vs CAF-NA |
3V ∼ PD * phenotype | PD | 1 | 0.1236 | 0.1236 | 13.933 | 0.0004*** |
| Phenotype | 1 | 0.0052 | 0.0052 | 0.591 | 0.4458 | ||
| PD * phenotype | 1 | 0.1590 | 0.1590 | 17.924 | 0.0001*** | ||
|
CC Contrast CON-NA Vs CAF-NA |
CC ∼ PD * phenotype | PD | 1 | 0.2089 | 0.2089 | 16.790 | 0.0001*** |
| Phenotype | 1 | 0.0132 | 0.0132 | 1.063 | 0.3076 | ||
| PD * phenotype | 1 | 0.1207 | 0.1207 | 9.700 | 0.0030** | ||
|
HT Contrast CON-NA Vs CAF-NA |
HT ∼ PD * phenotype | PD | 1 | 0.0536 | 0.0536 | 7.470 | 0.0087** |
| Phenotype | 1 | 0.0006 | 0.0006 | 0.088 | 0.7678 | ||
| PD * phenotype | 1 | 0.0805 | 0.0804 | 11.213 | 0.0015** | ||
|
CPu Contrast CON-NA Vs CON-A |
CPu ∼ PD * phenotype | PD | 1 | 0.0285 | 0.0284 | 3.861 | 0.0551 |
| Phenotype | 1 | 0.0804 | 0.0803 | 10.902 | 0.0017** | ||
| PD * phenotype | 1 | 0.1311 | 0.1311 | 17.790 | 0.0001*** | ||
|
AMY Contrast CON-NA Vs CON-A |
AMY ∼ PD * phenotype | PD | 1 | 0.0104 | 0.0104 | 2.258 | 0.1394 |
| Phenotype | 1 | 0.0232 | 0.0232 | 5.033 | 0.0294* | ||
| PD * phenotype | 1 | 0.1072 | 0.1072 | 23.261 | 0.0001*** | ||
|
FrA Contrast CON-NA Vs CON-A |
FrA ∼ PD * phenotype | PD | 1 | 0.0214 | 0.0214 | 5.486 | 0.0232* |
| Phenotype | 1 | 0.0361 | 0.0361 | 9.246 | 0.0037** | ||
| PD * phenotype | 1 | 0.0364 | 0.0364 | 9.344 | 0.0036** | ||
|
PML Contrast CON-NA Vs CON-A |
FrA ∼ PD * phenotype | PD | 1 | 0.0673 | 0.0673 | 17.423 | 0.0001*** |
| Phenotype | 1 | 0.0036 | 0.0036 | 0.946 | 0.3354 | ||
| PD * phenotype | 1 | 0.0685 | 0.0685 | 17.735 | 0.0001*** |
Behavioral traits in the offspring of mice prenatally exposed to HED. PD = distance traveled during open field.
*
<0.05.
**
<0.01.
***
<0.001.