TABLE 2.

Age-stratified multivariate Cox regression analyses for all-cause mortality using serum uric acid as a continuous independent variable

	Hazard ratio	95% CI (lower bound)	95% CI (upper bound)	P
Age 65–74 years
Uric acid (mg/dl)a	1.185	1.142	1.230	<0.001
Uric acid (mg/dl)	1.169	1.107	1.235	<0.001
Male sex	1.944	1.662	2.273	<0.001
Hypertension	1.085	0.924	1.273	0.321
Alcohol use	2.162	1.663	2.810	<0.001
Creatinine (mg/dl)	1.228	0.985	1.531	0.068
Total cholesterol (mg/dl)	0.999	0.997	1.001	0.229
Diuretic use	0.920	0.728	1.162	0.483
Diabetes	1.726	1.450	2.054	<0.001
Chronic kidney disease	0.882	0.733	1.062	0.185
Heart failure	2.096	1.788	2.457	<0.001
Age 75+ years
Uric acid (mg/dl)a	1.064	1.024	1.105	0.002
Uric acid (mg/dl)	1.009	0.570	1.064	0.730
Male sex	1.340	1.140	1.574	<0.001
Hypertension	1.184	1.016	1.380	0.030
Alcohol use	2.352	1.811	3.054	<0.001
Creatinine (mg/dl)	0.964	0.768	1.210	0.752
Total cholesterol (mg/dl)	0.997	0.995	0.999	0.001
Diuretic use	0.619	0.493	0.777	<0.001
Diabetes	1.591	1.332	1.900	<0.001
Chronic kidney disease	0.899	0.735	1.100	0.301
Heart failure	2.133	1.807	2.518	<0.001

^aUnadjusted.