Figure 4.

Illustration of the annotation code logic and the second phase of mapping. This figure illustrates a simplified version of the three-step approach taken by the code to match extracted end points to terms from each of the three controlled vocabularies. The code completes step 3 three times, each time replacing which controlled vocabulary it searches for matches. The code then pulls in the terms from the other two controlled vocabularies that are linked in the crosswalk to any found matches. During this process if a UMLS term is not found, the code will pull in BfR terms based on an OECD match or an OECD term based on a BfR match. After the code runs on the three controlled vocabularies, the code will use the crosswalk between vocabularies to search for matches. After the conclusion of the process, the end points may have more than a single match (e.g., a UMLS term can have many matches in OECD or BfR). Note: BfR, German Federal Institute for Risk Assessment; OECD, Organization for Economic Co-operation and Development; UMLS, Unified Medical Language System.