Table .
Echocardiographic Parameters in a Murine Model of Ischemia/Reperfusion (I/R) on Day 14 After I/R Injury
Variables | Sham | I/R | |
---|---|---|---|
Vehicle | Vehicle | Deferasirox+CsA | |
n | 6 | 9 | 8 |
LVEDD, mm | 3.4±0.3 | 4.4±0.4* | 3.9±0.4† |
LVESD, mm | 2.1±0.3 | 3.6±0.5* | 2.8±0.4‡ |
LVEF, % | 70±4 | 39±9* | 53±5§ |
Data are presented as the mean±SEM. Statistical significance was determined using 1‐way ANOVA with Tukey post hoc test. CsA indicates cyclosporin A; LVEDD, left ventricular end‐diastolic diameter; LVEF, left ventricular ejection fraction; and LVESD, left ventricular end‐systolic diameter.
P<0.001 vs. sham+vehicle.
P<0.05
P<0.01
P<0.001 vs I/R+vehicle.