Table 1.
Parent clinical trial and sub‐study cohort demographic variables and demographic variables by postoperative delirium status.
| Demographic and clinical variables | Postoperative delirium (POD) status | |||||
|---|---|---|---|---|---|---|
| Parent trial cohort | Sub‐study cohort | p‐value | POD | No POD | p‐value | |
| N (%) | 383 (100%) | 298 (77.8%) | 65/277 a (23.5%) | 212/277 a (76.5%) | ||
| Sex = Female (%) | 147 (38.4%) | 117 (39.3%) | p = 0.88 | 23 (21.7%) | 83 (78.3%) | p = 0.69 |
| Age (mean; SD) | 73.89 (6.7) | 74.02 (6.7) | p = 0.69 | 75 (6.7) | 74 (6.8) | p = 0.28 |
| Race (%) | p = 0.99 | p = 0.37 | ||||
| Asian | 5 (1.3%) | 4 (1.3%) | 1 (25.0%) | 3 (75.0%) | ||
| Black | 19 (5.0%) | 14 (4.7%) | 1 (8.3%) | 11 (91.6%) | ||
| Not reported | 5 (1.3%) | 4 (1.3%) | 2 (50.0%) | 2 (50.0%) | ||
| White | 352 (91.9%) | 276 (92.6%) | 61 (23.7%) | 196 (76.3%) | ||
| Surgical device (%) | p = 0.98 | p = 0.43 | ||||
| Embol‐X (filtration device) | 133 (34.7%) | 103 (34.6%) | 26 (26.5%) | 72 (73.5%) | ||
| CardioGard (suction device) | 118 (30.8%) | 90 (30.2%) | 21 (25.0%) | 63 (75.0%) | ||
| Cannula control | 132 (34.5%) | 105 (35.2%) | 18 (18.9%) | 77 (81.1%) | ||
| History of stroke (%) | 21 (5.5%) | 15 (5.0%) | p = 0.93 | 4 (30.8%) | 9 (69.2%) | p = 0.76 |
| History of hypertension (%) | 320 (83.6%) | 245 (82.2%) | p = 0.72 | 59 (26.1%) | 167 (73.9%) | p = 0.04 |
t‐test were used for continuous variables and Fisher test for discrete variables.
a
Percentages reflect number of study patients in each group, minus patients with incomplete POD outcome data (n = 16) or screened positive for delirium prior to surgery (n = 5).