Table 3.
Visual acuity, central macular thickness, and fluorescein angiography score before and after tocilizumab therapy in seven patients with non-infectious uveitis.
| VA (ETDRS) |
AC Cells (0–4) |
AC Flare (0–4) |
VH (0–4) |
CST (μm) |
FA Score |
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pt no | Eye | Int | 3rd cycle | Fnl | Int | 3rd cycle | Fnl | Int | 3rd cycle | Fnl | Int | 3rd cycle | Fnl | Int | 3rd cycle | Fnl | Int | 3rd cycle | Fnl |
|
| |||||||||||||||||||
| 1 | OD | 65 | 80 | 80 | 0 | 0 | 0 | 2 | 0.5 | 0.5 | 0.5 | 0 | 0 | 514 | 289 | 283 | 16 | 0 | 0 |
| 2 | OD | 35 | 35 | 35 | 0 | 0 | 0 | 2 | 1 | 1 | 2 | 1 | 0.5 | 334 | N/A | 333 | 12 | 5 | 3 |
| 3 | OS | 70 | 80° | 80 | 1 | 0° | 0 | 2 | 1° | 1 | 1* | 1°,* | 1* | N/A | 321° | 321 | N/A | 5° | 3 |
| 4 | OD | 25 | 25 | 25 | 0 | 0 | 0 | 2 | 1 | 1 | 0.5 | 0 | 0 | 328 | N/A | 315 | 17 | 6 | 4 |
| 5 | OD | 85 | 85° | 85 | 0 | 0° | 0 | 1 | 0.5° | 0.5 | 0.5 | 0° | 0 | N/A | 263° | 247 | 14 | 5° | 3 |
| 5 | OS | 75 | 75° | 80 | 0 | 0° | 0 | 0.5 | 0.5° | 0.5 | 0.5 | 0.5° | 0.5 | N/A | 273° | 259 | 14 | 12° | 9 |
| 6 | OD | 25 | 35 | 35 | 0 | 0 | 0 | 1 | 1 | 1 | 1* | 1* | 1* | 296 | 276 | 264 | 13 | 6 | 2 |
| 6 | OS | 70 | 70 | 70 | 0 | 0 | 0 | 1 | 0.5 | 0.5 | 0 | 0 | 0 | 293 | 285 | 267 | 6 | 2 | 3 |
| 7 | OD | 55 | 55 | 55 | 1 | 0 | 0 | 1 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 524 | 378 | 373 | 16 | 8 | 7 |
| 7 | OS | 85 | 85 | 85 | 2 | 0 | 0 | 2 | 0.5 | 0.5 | 0 | 0 | 0 | 322 | 319 | 320 | 5 | 2 | 2 |
Pt: patient, TCZ: tocilizumab, VA: visual acuity, CST: central subfield thickness, FA: fluorescein angiography, Int: initial, Fnl: final.
After 3 cycles of 4 mg TCZ infusions.
Presence of cataract.