TABLE 2.

≥ Grade 3 toxicities observed in all (N=12) evaluable patients

		# of Patients in Cycle 1
		By Maximum Grade
		Grade 3	Grade 4
Hematologic Type	Toxicity Type
Hematologic	Anemia	8
	Lymphocyte count decreased	1	8
	Neutrophil count decreased	1	4
	Platelet count decreased		5
	White blood cell decreased		8
Non-Hematologic
	Anorexia	1
	Febrile neutropenia	2	1
	Fever	2
	GGT increased*		1
	Hypertension*	1
	Hypertriglyceridemia		1
	Hypokalemia	3	1
	Hypophosphatemia	2
	Hypoxia*	1
	Nausea	1
	Proteinuria*	1
	Sepsis	3
	Weight loss*	1

^*dose limiting toxicity