Figure 1.

Experimental design. A: experimental design. The animals were distributed into five experimental groups: control group (CTL), obese mice (OB), time-restricted feeding (TRF), resistance exercise training (RT), and TRF + RT. The TRF, RT, and TRF + RT were submitted to time-restricted feeding (TRF) and/or resistance exercise training (RT) interventions for 8 wks for further analysis. B: the TRF protocol was performed during the animals’ light and dark cycles. CLAMS, Comprehensive Laboratory Animal Monitoring System; GTT, glucose tolerance test; ITT, insulin tolerance test; MVCC, maximum voluntary carrying capacity; ZT, zeitgeber time.