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. Author manuscript; available in PMC: 2024 Feb 13.
Published in final edited form as: J Card Fail. 2023 Sep 26;29(10):1412–1451. doi: 10.1016/j.cardfail.2023.07.006

Table 11.

Trends in HF Hospitalizations by Age

Category Timespan Trend Source
Age at Hospitalization Median [IQR]
HFrEF 2008–2018 74.0 [74.0–83.0] to 71.0 [59.0–81.0], p<0.001 NIS12
HFpEF 2008–2018 78.0 [67.0–86.0] to 77.0 [66.0–85.0], p<0.001 NIS12
Hospitalization Rates Annual Percentage Change
Age ≥ 65 years 2004–2014 −4.5%, p<0.05 NIS2
Age ≥ 65 years 2014–2018 2.8%, p<0.05 NIS2
Age 18–64 years 2004–2013 −2.3%, p<0.05 NIS2
Age 18–64 years 2013–2018 7.0%, p<0.05 NIS2
In-Hospital Mortality Mortality Rate
Age 18–34 years 2002–2016 2.2% to 1.6%, p=0.13 NIS13
Age 35–44 years 2002–2016 1.5% to 1.0%, p=0.01 NIS13
Age 45–54 years 2002–2016 1.7% to 1.3%, p<0.001 NIS13
Age 55–64 years 2002–2016 2.4% to 1.7%, p<0.001 NIS13
Age 65–74 years 2002–2016 3.5% to 2.3%, p<0.001 NIS13
Age ≥ 75 years 2002–2016 5.8% to 3.8%, p<0.001 NIS13

HF = heart failure; HFrEF = heart failure with reduced ejection fraction; HFpEF = heart failure with preserved ejection fraction; IQR = interquartile range; NIS = Nationwide Inpatient Sample.

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Clark KAA, Reinhardt SW, Chouairi F, Miller PE, Kay B, Fuery M, et al. Trends in Heart Failure Hospitalizations in the US from 2008 to 2018 .J Card Fail. 2022 Feb;28(2):171–80.

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