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Effect of endogenous LT synthesis inhibition on AM phagocytosis of K. pneumoniae. AMs were pretreated with medium alone, zileuton (10 μM), or MK-886 (1 μM) for 15 min before the addition of opsonized K. pneumoniae. Data are expressed as the mean phagocytic index (percentage of control) ± SE (n = 4). ∗, P < 0.05 with respect to the control by ANOVA.
